N-Acetyl Glucosamine (NAG)
C₈H₁₅NO₆
Hydration Hero & Skin Barrier Supporter for Plump, Resilient Skin
Source & Overview
N-Acetyl Glucosamine (NAG) is a naturally occurring amino sugar derived from chitin, found in shellfish exoskeletons (e.g., shrimp, crab) or fermented from plant sources (vegan-friendly options). A precursor to hyaluronic acid and a key component of the skin’s extracellular matrix, it’s revered for its ability to repair, hydrate, and brighten.
Key Benefits for Skin
✨ Barrier Repair:
- Strengthens the skin’s moisture barrier by boosting ceramide synthesis, reducing transepidermal water loss (TEWL).
✨ Hydration Boost: - Enhances hyaluronic acid production for plumper, dewier skin.
✨ Brightening: - Inhibits tyrosinase activity, reducing melanin production to fade dark spots and even skin tone (gentler than kojic acid).
✨ Anti-Aging: - Stimulates collagen and elastin, improving elasticity and smoothing fine lines.
✨ Soothing: - Calms redness, irritation, and sensitivity (ideal for rosacea or eczema-prone skin).
How to Use in Skincare
- Concentration:
- 2–5% in serums, moisturizers, or toners.
- Layering:
- Pairs beautifully with hyaluronic acid (hydration), niacinamide (barrier repair), and vitamin C (brightening).
- Safe to use with retinol to minimize irritation.
- Application:
- Apply after cleansing, before heavier creams. Use AM/PM.
Safety
- Allergies: Shellfish-derived NAG may trigger allergies—opt for vegan/fermented versions if sensitive.
- Gentle Enough: Safe for all skin types, including sensitive/acne-prone.
- Storage: Stable in formulations; no special handling required.
